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Umbilical Cord Blood Banking and Transplantation

Regular price Rs.1,900
Sale price Rs.2,500

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Estimate delivery times: 03-05 Working days In Pakistan

Return within 45 days of purchase. Duties & taxes are non-refundable.

Umbilical Cord Blood Banking and Transplantation
Umbilical Cord Blood Banking and Transplantation
Regular price Rs.1,900
Sale price Rs.2,500

My interest in blood stem cells and cord blood dates back to my fellowship in Pediatric Hematology/Oncology at Duke. During my fellowship, I worked on the development of novel antileukemia drugs based on analogs of purine metabolism and treated a teenage patient with refractory T‐cell acute lymphoblastic leukemia with a novel anti‐leukemia drug, 2′‐deoxycoformycin, an inhibiter of adenosine deaminase. During 5‐day course of therapy, his leukemia converted from a T‐lymphoid to a myeloid phenotype before our eyes 1. I subsequently established a cell line from these leukemic cells, DU‐528 and, ultimately, proved that this leukemia arose from a common lymphoid‐myeloid progenitor cell 2, which then led me to the study of hematopoietic stem and progenitor cells. Hal Broxmeyer, who would go on to become a pioneer in the use of cord blood as a source of donor cells for bone marrow reconstitution, mentored me as I studied normal and malignant hematopoietic stem cells isolated from bone marrow, fetal liver, and umbilical cord blood. In the clinic, I cared for children with leukemias and blood dyscrasias, including a young boy named Matthew Farrow from Salisbury, NC, with Fanconi anemia (FA) and evolving bone marrow failure. This genetic disease, which arises from a mutation in genes that encode the enzymes responsible for DNA repair, is associated with a host of serious medical and developmental problems. The prognosis for Matthew's condition was stark: most children with Fanconi anemia died of bone marrow failure or leukemia in the first decade of life, unless treated with a bone marrow transplant from a human leukocyte antigen (HLA)‐matched donor.

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Returns will be accepted for up to 10 days of Customer’s receipt or tracking number on unworn items. You, as a Customer, are obliged to inform us via email before you return the item, only in the case of:

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